Denis Lacombe MD. MSc has a long-standing career in clinical research. As the Chief Executive Officer of the European Organisation for Research and Treatment of Cancer (EORTC), the largest European non-governmental multidisciplinary cancer clinical research infrastructure, Dr Lacombe has a unique grasp on EU matters related to research in health. Author of more than 150 publications, in cancer research and related matters, he has also developed a specific expertise in European policy affairs, advocating for reforms in clinical research and health care systems building clinically robust end-points relevant for patients in care as well as ensuring sustainability and access to therapeutic innovation to all. Dr Lacombe has contributed to many conferences and events addressing EU research in health.